FGF21 anticorps (Internal Region)

N° du produit ABIN374880

Détail du produit anti-FGF21 anticorps

Antigène: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF21 est non-conjugé

Application: Western Blotting (WB)

Séquence: CQRPDGALYG SLH

Specificité: This antibody detects FGF21.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogène: Peptide from the internal region of the protein sequence according to NP_061986.1.

Information d'application

Indications d'application: Peptide ELISA: limit dilution 1: 2000. Western blot: 1-3 μg/mL. Approx 22 kDa band observed in Human Liver lysates (calculatedMW of 22.2 kDa according to NP_061986.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-FGF21 (ABIN374880)

Cyphert, Ge, Kohan, Salati, Zhang, Hillgartner: "Activation of the farnesoid X receptor induces hepatic expression and secretion of fibroblast growth factor 21." dans: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25123-38, (2012) (PubMed).

Détails sur FGF21

Antigène: FGF21 (Fibroblast Growth Factor 21 (FGF21))

Autre désignation: FGF21 (FGF21 Produits)

Synonymes: anticorps FGF21, anticorps fibroblast growth factor 21, anticorps FGF21, anticorps fgf21, anticorps Fgf21

Sujet: FGF21 is a growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF21, in the presence of betaKlotho as a protein cofactor, signals through the FGFR 1c and 4 receptors and stimulates insulin independent glucose uptake by adipocytes.Synonyms: FGF-21, Fibroblast growth factor 21

ID gène: 26291, 9606

UniProt: Q9NSA1

Pathways: Signalisation RTK