IGFBP4 anticorps (C-Term)

N° du produit ABIN374952

Détail du produit anti-IGFBP4 anticorps

Antigène: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Épitope: C-Term

Reactivité: Humain, Souris, Boeuf (Vache)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IGFBP4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to IGFBP4.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence KGELDCHQLADSFRE, from the C Terminus of the protein sequence

Information d'application

Indications d'application: Peptide ELISA: 1/8000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IGFBP4

Antigène: IGFBP4 (Insulin-Like Growth Factor Binding Protein 4 (IGFBP4))

Autre désignation: IGFBP4 (IGFBP4 Produits)

Synonymes: anticorps IGFBP4, anticorps igfbp4, anticorps BP-4, anticorps HT29-IGFBP, anticorps IBP4, anticorps IGFBP-4, anticorps AI875747, anticorps Deb2, anticorps IGF-BP4, anticorps IBP-4, anticorps insulin like growth factor binding protein 4, anticorps insulin-like growth factor-binding protein 4, anticorps insulin-like growth factor binding protein 4, anticorps IGFBP4, anticorps LOC100136305, anticorps LOC100194498, anticorps igfbp4, anticorps Igfbp4

Sujet: IGFBP4 (Insulin like growth factor binding protein 4) is produced from a DNA sequence encoding the human IGFBP4 protein. Mature human IGFBP4 has a calculated molecular mass of approximately 26 kDa. Due to glycosylation, the recombinant protein migrates as a 32 kDa and 25 kDa protein under reducing and non reducing conditions, respectively. Human IGFBP4 has a potential N-linked glycosylation site and shares approximately 90 % amino acid sequence identity with both mouse and rat IGFBP4. IGFBP4 is a member of the superfamily of insulin-like growth factor (IGF) binding proteins which include six high affinity IGF binding proteins (IGFBP) and at least four low affinity binding proteins referred to as IGFBP related proteins (IGFBPrP). IGFBP4 functions as an inhibitor of IGF action and its main function may be to protect cells from overstimulation by IGFs or to allow activation of alternate transmembrane signaling pathways that are inhibited by IGF exposure. IGFBP4 is expressed in multiple tissues including adrenal, testis, spleen, heart, lung, kidney, liver, stomach, hypothalamus, and brain cortex.Synonyms: IBP-4, IBP4, IGF-binding protein 4, IGFBP-4, Insulin-like growth factor-binding protein 4

ID gène: 3487

NCBI Accession: NP_001543

UniProt: P22692

Pathways: Signalisation WNT, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process