TFEB anticorps (Internal Region)
-
- Antigène Voir toutes TFEB Anticorps
- TFEB (Transcription Factor EB (TFEB))
-
Épitope
- Internal Region
-
Reactivité
- Humain, Souris, Rat, Chien
-
Hôte
- Chèvre
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp TFEB est non-conjugé
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes TFEB and is not expected to cross-react with TFE3 and MITF.
- Réactivité croisée (Details)
-
Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. - Purification
- Immunoaffinity Chromatography
- Immunogène
- Peptide with sequence C-QKDLQKSRELENH, from the internal region of Human TFEB (NP_009093.1). Genename: TFEB
- Top Product
- Discover our top product TFEB Anticorps primaire
-
-
- Indications d'application
-
Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, , pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- TFEB (Transcription Factor EB (TFEB))
- Autre désignation
- TFEB (TFEB Produits)
- Synonymes
- anticorps TFEB, anticorps tcfeb, anticorps MGC145796, anticorps alphatfeb, anticorps ALPHATFEB, anticorps BHLHE35, anticorps TCFEB, anticorps Tcfeb, anticorps bHLHe35, anticorps transcription factor EB, anticorps TFEB, anticorps tfeb, anticorps Tfeb
- Sujet
- Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.Synonyms: Transcription factor EB
- ID gène
- 7942, 9606
- UniProt
- P19484
-