ABCC5 anticorps (N-Term)

N° du produit ABIN375007

Détail du produit anti-ABCC5 anticorps

Antigène: ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: KDIDIGKEYI IP-C

Specificité: This antibody is expected to recognize both reported isoforms (NP_005679.2, NP_001018881.1).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the N Terminus of the protein sequence according to NP_005679.2, NP_001018881.1. Genename: ABCC5

Information d'application

Indications d'application: Peptide ELISA: Detection Limit: 1/32000. Wetsren Blot: 0.5-1.5 μg/mL. Approx.150 kDa band observed in Human Brain (FrnotalCortex) and Mouse Brain lysates. Immunohistochemistry on Paraffin Embedded Sections: 4-6 μg/mL. In paraffin embedded Human Kidney shows membranous staining in DCT.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ABCC5

Antigène: ABCC5 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))

Autre désignation: ABCC5 / MRP5 (ABCC5 Produits)

Synonymes: anticorps ABC33, anticorps EST277145, anticorps MOAT-C, anticorps MOATC, anticorps MRP5, anticorps SMRP, anticorps pABC11, anticorps 2900011L11Rik, anticorps AI132311, anticorps Abcc5a, anticorps Abcc5b, anticorps Mrp5, anticorps abc33, anticorps abcc5, anticorps moat-c, anticorps moatc, anticorps mrp5, anticorps pabc11, anticorps smrp, anticorps ATP binding cassette subfamily C member 5, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 5, anticorps ATP binding cassette subfamily C member 5 L homeolog, anticorps ABCC5, anticorps Abcc5, anticorps abcc5.L

Sujet: MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.Synonyms: ATP-binding cassette sub-family C member 5, MOAT-C, Multi-specific organic anion transporter C, Multidrug resistance-associated protein 5, SMRP, pABC11

ID gène: 10057, 9606

UniProt: O15440

Pathways: Glycosaminoglycan Metabolic Process