NR1H4 anticorps (Internal Region)

N° du produit ABIN375197

Détail du produit anti-NR1H4 anticorps

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Épitope: Internal Region

Reactivité: Humain, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1H4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: KSCREKTELT PDQQ

Specificité: This antibody recognizes HRR1.

Réactivité croisée (Details): Species reactivity (expected):Canine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence Genename: NR1H4

Information d'application

Indications d'application: ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur NR1H4

Antigène: NR1H4 (Nuclear Receptor Subfamily 1, Group H, Member 4 (NR1H4))

Autre désignation: NR1H4 / FXR (NR1H4 Produits)

Synonymes: anticorps zgc:110190, anticorps zgc:92742, anticorps NR1H4, anticorps BAR, anticorps FXR, anticorps HRR-1, anticorps HRR1, anticorps RIP14, anticorps AI957360, anticorps Fxr, anticorps Rxrip14, anticorps nuclear receptor subfamily 1, group H, member 5 S homeolog, anticorps nuclear receptor subfamily 1, group H, member 4, anticorps nuclear receptor subfamily 1 group H member 4, anticorps nr1h5.S, anticorps nr1h4, anticorps NR1H4, anticorps Nr1h4

Sujet: Bile Acid Receptor NR1H4 is a receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. It represses the transcription of the cholesterol 7 alpha hydroxylase gene and activates the intestinal bile acid binding protein. The NR1H4 gene encodes a protein that has a central role in lipid homeostasis and also regulates carbohydrate metabolism.Synonyms: BAR, Bile acid receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, HRR1, Nuclear receptor subfamily 1 group H member 4, RIP14, Retinoid X receptor-interacting protein 14

ID gène: 9971

NCBI Accession: NP_001193906

UniProt: Q96RI1

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Carbohydrate Metabolic Process