BCL10 anticorps (AA 122-168)

N° du produit ABIN379257

L’anticorps Souris Monoclonal anti-BCL10 a été validé pour . Il convient pour détecter BCL10 dans des échantillons de Humain.

Aperçu rapide pour BCL10 anticorps (AA 122-168) (ABIN379257)

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL10 est non-conjugé

Application: Veuillez nous consulter SVP

Clone: 151

Détail du produit anti-BCL10 anticorps

Épitope: AA 122-168

Specificité: Monoclonal Anti-Bcl-10 reacts specifically with human Bcl-10. The epitope recognized by the antibody resides within amino acids 122-168 of human Bcl-10 Molecule. Bcl-10, also designated as CIPER, mE10, cE10, CARMEN, and CLAP, is an N-terminal CARD (Caspase Recruitment Domain) containing protein. It is a cellular homologue of the equine herpesvirus-2 protein E-10 (vCLAP). Bcl-10 was implicated in the regulation of apoptosis by interacting with caspase 9, enhancing procaspase 9 processing, and triggering its activation when overexpressed in the cell. Bcl-10 cellular overexpression induces JNK, p38, and NF-kB activation. Deregulation of Bcl-10 expression is also demonstrated to be involved in cellular oncogenesis.

Purification: Protein G purified

Immunogène: Human recombinant Bcl-10.

Isotype: IgG1

Information d'application

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Buffer contains: 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur BCL10

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Autre désignation: BCL10 / BCL-10

Sujet: Name/Gene ID: BCL10
Family: Apoptosis

Synonyms: BCL10, Bcl-10, B-cell CLL/lymphoma 10, B-cell lymphoma/leukemia 10, CARMEN, CARD-like apoptotic protein, CCARMEN, C-E10, CIPER, Cellular-E10, HCLAP, Cellular homolog of vCARMEN, CLAP, ME10

ID gène: 8915

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins