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eIF4EBP1 anticorps (pThr36)
EIF4EBP1
Reactivité: Humain
DB
Hôte: Lapin
Polyclonal
RB11405
unconjugated
N° du produit ABIN2839697
Détail du produit anti-eIF4EBP1 anticorps
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Antigène
Voir toutes eIF4EBP1 (EIF4EBP1) Anticorps
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Épitope
Tous les épitopes à travers eIF4EBP1 Anticorps.
pThr36
Reactivité
Toutes les réactivités sur eIF4EBP1 Anticorps
Humain
Hôte
Toutes les hôtes sur eIF4EBP1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur eIF4EBP1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers eIF4EBP1 Anticorps
Cet anticorp eIF4EBP1 est non-conjugé
Application
Tous les applications à travers eIF4EBP1 Anticorps.
Dot Blot (DB)
Homologie
B, M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This EIF4EBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T36 of human EIF4EBP1.
Clone
RB11405
Isotype
Ig Fraction
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Alternatives
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Information d'application
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Indications d'application
DB: 1:500
Restrictions
For Research Use only
Stockage
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Détails sur eIF4EBP1
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Antigène
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Autre désignation
EIF4EBP1 (EIF4EBP1 Produits )
Synonymes
anticorps 4E-BP1, anticorps 4EBP1, anticorps BP-1, anticorps PHAS-I, anticorps 4e-bp1, anticorps AA959816, anticorps 153432_at, anticorps 43-BP, anticorps 4E-BP, anticorps 4EBP, anticorps 4e-bp, anticorps 4eBP, anticorps 4ebp, anticorps BcDNA.HL08053, anticorps BcDNA:HL08053, anticorps CG8846, anticorps CT8705, anticorps Dm 4E-BP, anticorps Dmel\\CG8846, anticorps Phas1, anticorps Thor/EIF4EBP, anticorps anon-WO0172774.158, anticorps d4E-BP, anticorps d4E-BP1, anticorps d4EBP, anticorps d4e-bp, anticorps d4eBP, anticorps dthor, anticorps eIF4E-BP, anticorps l(2)06270, anticorps l(2)k07736, anticorps l(2)k13517, anticorps pp20, anticorps thor, anticorps EIF4EBP1, anticorps fc04h09, anticorps wu:fc04h09, anticorps zgc:64137, anticorps eukaryotic translation initiation factor 4E binding protein 1, anticorps CG8846 gene product from transcript CG8846-RA, anticorps EIF4EBP1, anticorps Eif4ebp1, anticorps Thor, anticorps eif4ebp1
Sujet
EIF4EBP1 is a member of a family of translation repressor proteins. This protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. It is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Poids moléculaire
12580
ID gène
1978
NCBI Accession
NP_004086
UniProt
Q13541
Pathways
Signalisation MAPK , Signalisation PI3K-Akt , Signalisation RTK , AMPK Signaling , Regulation of Cell Size , BCR Signaling
Vus récemment
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