PTPRE anticorps (C-Term)

N° du produit ABIN392837

Détail du produit anti-PTPRE anticorps

Antigène: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Épitope: AA 558-589, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRE est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This PTP epsilon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-589 amino acids from the C-terminal region of human PTP epsilon.

Clone: RB0551

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-PTPRE (ABIN392837)

Zheng, Resnick, Shalloway: "Apoptosis of estrogen-receptor negative breast cancer and colon cancer cell lines by PTP alpha and src RNAi." dans: International journal of cancer, Vol. 122, Issue 9, pp. 1999-2007, (2008) (PubMed).

Détails sur PTPRE

Antigène: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Autre désignation: PTP epsilon (PTPRE Produits)

Synonymes: anticorps ptpra, anticorps HPTPE, anticorps PTPE, anticorps R-PTP-EPSILON, anticorps PTPe, anticorps PTPepsilon, anticorps RPTPepsilon, anticorps protein tyrosine phosphatase, receptor type E L homeolog, anticorps protein tyrosine phosphatase, receptor type E, anticorps protein tyrosine phosphatase, receptor type, E, anticorps ptpre.L, anticorps PTPRE, anticorps Ptpre

Sujet: PTPepsilon is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of the gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.

Poids moléculaire: 80642

ID gène: 5791

NCBI Accession: NP_006495, NP_569119

UniProt: P23469