PTPRE anticorps

N° du produit ABIN7167503

Détail du produit anti-PTPRE anticorps

Antigène: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPRE est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Receptor-type tyrosine-protein phosphatase epsilon protein

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PTPRE

Antigène: PTPRE (Protein tyrosine Phosphatase, Receptor Type, E (PTPRE))

Autre désignation: PTPRE (PTPRE Produits)

Synonymes: anticorps ptpra, anticorps HPTPE, anticorps PTPE, anticorps R-PTP-EPSILON, anticorps PTPe, anticorps PTPepsilon, anticorps RPTPepsilon, anticorps protein tyrosine phosphatase, receptor type E L homeolog, anticorps protein tyrosine phosphatase, receptor type E, anticorps protein tyrosine phosphatase, receptor type, E, anticorps ptpre.L, anticorps PTPRE, anticorps Ptpre

Sujet:

Background: Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake.Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca2+.

Aliases: DKFZp313F1310 antibody, FLJ57799 antibody, FLJ58245 antibody, HPTPE antibody, Protein tyrosine phosphatase epsilon antibody, Protein tyrosine phosphatase receptor type E antibody, Protein tyrosine phosphatase receptor type epsilon antibody, Protein tyrosine phosphatase receptor type epsilon polypeptide antibody, Protein-tyrosine phosphatase epsilon antibody, PTPE antibody, Ptpre antibody, PTPRE_HUMAN antibody, R PTP Epsilon antibody, R-PTP-epsilon antibody, Receptor-type tyrosine-protein phosphatase epsilon antibody

UniProt: P23469