CD42b anticorps (AA 19-129)

N° du produit ABIN394943

Détail du produit anti-CD42b anticorps

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Épitope: AA 19-129

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD42b est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Réactivité croisée (Details): Human: ~~ Positive

Purification: This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogène:

Antigen Type: Recombinant Protein

Target/Specificity: GP1BA (AAH27955, 19 a.a. ~ 128 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1C6

Isotype: IgG2a kappa

Information d'application

Indications d'application: ELISA ~~ 1ug/ml~3ng/ml Western blot ~~ 1:500~1000

Restrictions: For Research Use only

Stockage

Buffer: Clear, colorless solution in phosphate buffered saline,  pH 7.2 .

Stock: 4 °C/-20 °C

Stockage commentaire: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles

Date de péremption: 6 months

Détails sur CD42b

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Autre désignation: GP1BA (GP1BA Produits)

Synonymes: anticorps BDPLT1, anticorps BDPLT3, anticorps BSS, anticorps CD42B, anticorps CD42b-alpha, anticorps DBPLT3, anticorps GP1B, anticorps GPIbA, anticorps VWDP, anticorps GP1BA, anticorps GPIba, anticorps GPIbalpha, anticorps glycoprotein Ib platelet alpha subunit, anticorps glycoprotein Ib (platelet), alpha polypeptide, anticorps glycoprotein 1b, alpha polypeptide, anticorps GP1BA, anticorps Gp1ba

Sujet:

Other Names: Platelet glycoprotein Ib alpha chain, GP-Ib alpha, GPIb-alpha, GPIbA, Glycoprotein Ibalpha, Antigen CD42b-alpha, CD42b, Glycocalicin, GP1BA

Gene Description: glycoprotein Ib (platelet), alpha polypeptide

Gene Summary: Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq

Poids moléculaire: 68955 DA

ID gène: 2811

UniProt: P07359