GLI3 anticorps (AA 41-57)

N° du produit ABIN401281

Détail du produit anti-GLI3 anticorps

Antigène: GLI3 (GLI Family Zinc Finger 3 (GLI3))

Épitope: AA 41-57

Reactivité: Humain, Souris, Rat, Chien, Poulet, Singe, Chimpanzé, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GLI3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody is directed against Gli-3 protein.

Réactivité croisée (Details): Species reactivity (expected):Chimpanzee, squirrel Monkey, Xenopus laevis, Chicken, Canine (100 %).Mouse (94 %).Rat (88 %).
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide corresponding to amino acids 41-57 of Human Gli-3 protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/6,000-1/30,000. Western blot: 1/500-1/2,000. Immunohistochemistry on Paraffin Sections: 0.5 mg/mL-5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.12 M NaCl, pH 7.2, 0.09 % (w/v) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur GLI3

Antigène: GLI3 (GLI Family Zinc Finger 3 (GLI3))

Autre désignation: GLI3 (GLI3 Produits)

Synonymes: anticorps ACLS, anticorps GCPS, anticorps GLI3-190, anticorps GLI3FL, anticorps PAP-A, anticorps PAPA, anticorps PAPA1, anticorps PAPB, anticorps PHS, anticorps PPDIV, anticorps xgli3, anticorps AI854843, anticorps AU023367, anticorps Bph, anticorps Pdn, anticorps Xt, anticorps add, anticorps im:7142603, anticorps GLI3, anticorps GLI family zinc finger 3, anticorps GLI family zinc finger 3 L homeolog, anticorps GLI-Kruppel family member GLI3, anticorps GLI3, anticorps Gli3, anticorps gli3.L, anticorps gli3

Sujet: Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers. Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal. Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues, including lung, colon, spleen, placenta, testis, and myometrium. Defects in Gli-3 are the cause of Greig cephalo-polysyndactyly syndrome (GCPS), an autosomal dominant disorder-affecting limb and craniofacial development. Two isoforms of human Gli-3 have been reported. One is the fulllength protein at ~170-190 kDa and the other is a truncated isoform at ~80 kDa.Synonyms: GLI-3, Zinc finger protein GLI3

ID gène: 2737

NCBI Accession: NP_000159

UniProt: P10071

Pathways: Signalisation Hedgehog