CHEK1 anticorps (AA 312-327)
Aperçu rapide pour CHEK1 anticorps (AA 312-327) (ABIN401324)
Antigène
Voir toutes CHEK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 312-327
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Specificité
- This antibody is directed against yeast CHK1 protein.
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Purification
- Affinity chromatography
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Immunogène
- Synthetic peptide corresponding aa 312-327 of S. cerevisiae CHK1
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Isotype
- IgG
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Indications d'application
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ELISA: 1/2,000 - 1/10,000. Western Blot: 1/200 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.73 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Autre désignation
- CHK1
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Sujet
- CHK1 (also known as serine/threonine-protein kinase CHK1 and checkpoint kinase 1) is involved in cell cycle arrest when DNA damage has occurred or when unligated DNA is present. The kinase controls phosphorylation and abundance of PDS1 to prevent anaphase entry. Also helps prevent mitotic exit. CHK1 is localized within the nucleus.Synonyms: CHEK-1, CHEK1, CHK1 checkpoint homolog, Serine/threonine-protein kinase Chk1
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ID gène
- 852577
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NCBI Accession
- NP_009833
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UniProt
- P38147
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Pathways
- Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN
Antigène
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