ASAP1 anticorps (AA 777-787)

N° du produit ABIN401327

Détail du produit anti-ASAP1 anticorps

Antigène: ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))

Épitope: AA 777-787

Reactivité: Souris, Humain, Boeuf (Vache), Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASAP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (expected):Human, Chicken, Bovine, Canine, Rat, Chimpanzee.
Species reactivity (tested):Mouse.

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding to amino acids 777-787 of mouse ASAP1 protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/2,000 - 1/10,000. Western Blot: 1/500 - 1/2,000. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.95 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur ASAP1

Antigène: ASAP1 (ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))

Autre désignation: ASAP1 / DDEF1 (ASAP1 Produits)

Synonymes: anticorps AV239055, anticorps DEF-1, anticorps Ddef1, anticorps PAP, anticorps mKIAA1249, anticorps s19, anticorps AMAP1, anticorps CENTB4, anticorps DDEF1, anticorps PAG2, anticorps ZG14P, anticorps ASAP1, anticorps ddef1, anticorps Asap1, anticorps si:ch211-160i2.3, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain1, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain 1, anticorps toxic extracellular endopeptidase, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog, anticorps ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a, anticorps Asap1, anticorps ASAP1, anticorps asaP1, anticorps asap1, anticorps asap1.L, anticorps asap1a

Sujet: ASAP1 (also known as AMAP1, 130- kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein, PIP2-dependent ARF1 GAP,ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, Differentiation-enhancing factor 1, DEF-1) is an Arf-directed GTPase activating protein that is a substrate for the kinases Src and FAK and has been implicated in the regulation of membrane traffic, focal adhesions and invadopodia/podosomes. Phosphorylation of ASAP1 at tyrosine 782 has been found to affect enzymatic and some biological activities, including the function of invadopodia. ASAP1 is expressed in many tissues but is most abundant in the testis, brain, lung and spleen. A heightened expression was seen in the adipose tissue from obese (ob) and diabetic (db) animals. Multiple transcript variants have been reported for this protein.Synonyms: 130 kDa phosphatidylinositol 4, 5-biphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, AMAP1, ANK repeat and PH domain-containing protein 1, Arf-GAP with SH3 domain, CENTB4, Development and differentiation-enhancing factor 1, KIAA1249, PAG2, PIP2-dependent ARF1 GAP, ZG14P

ID gène: 10090

UniProt: Q9QWY8