MCM2 anticorps (AA 21-31)

N° du produit ABIN401335

Détail du produit anti-MCM2 anticorps

Antigène: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Épitope: AA 21-31

Reactivité: Humain, Souris, Rat, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody is directed against human MCM2 protein.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, S. cerevisiae.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Synthetic peptide corresponding to amino acids 21-31 of human MCM2 protein

Isotype: IgG

Information d'application

Indications d'application: ELISA: 1/10,000 - 1/50,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.77 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur MCM2

Antigène: MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

Autre désignation: MCM2 (MCM2 Produits)

Synonymes: anticorps CG7538, anticorps DmMCM2, anticorps DmMcm2, anticorps DmeMCM2, anticorps Dmel\\CG7538, anticorps MCM2, anticorps MCM2-7, anticorps MCM2_DROME, anticorps McM2, anticorps PCR3, anticorps dMCM2, anticorps l(3)rL074, anticorps XMcm2, anticorps bm28, anticorps ccnl1, anticorps cdc19, anticorps cdcl1, anticorps mitotin, anticorps cb737, anticorps chunp6905, anticorps BM28, anticorps CCNL1, anticorps CDCL1, anticorps D3S3194, anticorps MITOTIN, anticorps MCM7, anticorps AA959861, anticorps AW476101, anticorps Mcmd2, anticorps mKIAA0030, anticorps Minichromosome maintenance 2, anticorps minichromosome maintenance complex component 2, anticorps minichromosome maintenance complex component 2 L homeolog, anticorps Mcm2, anticorps mcm2, anticorps MCM2, anticorps mcm2.L

Sujet: MCM2, also called DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog or Nuclear Protein BM28) is one of the highly conserved minichromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the prereplication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by protein kinases CDC2 and CDC7. Double serines at positions 26 and 27 are conserved in rat and mouse. High homology >88 % to similar proteins from several other species. Expected broad reactivity to various lysates.Synonyms: BM28, CCNL1, CDCL1, DNA replication licensing factor MCM2, Minichromosome maintenance protein 2 homolog, Nuclear protein BM28

ID gène: 4171

NCBI Accession: NP_004517

UniProt: P49736

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA