SHP1 anticorps

N° du produit ABIN452175

Détail du produit anti-SHP1 anticorps

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SHP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes single 67 kDa PTP1-C in Human cells that express the enzyme and the SH2(C) domain

Attributs du produit: Synonyms: PTPN-6, HCP, PTP1C, EC=3.1.3.48, Protein-tyrosine phosphatase 1C, PTP-1C, SH-PTP1,Protein-tyrosine phosphatase SHP-1, Hematopoietic cell protein-tyrosine phosphatase,Tyrosine-protein phosphatase non-receptor type 6

Purification: Affinity chromatography on Protein G

Immunogène: Purified recombinant protein corresponding to full-length PTP1-C

Clone: PTY15

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SHP1

Antigène: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Autre désignation: PTPN6 (PTPN6 Produits)

Synonymes: anticorps HCPH, anticorps HPTP1C, anticorps PTP-1C, anticorps SH-PTP1, anticorps SHP-1, anticorps SHP-1L, anticorps SHP1, anticorps DRPLA, anticorps Hcph, anticorps Ptp1C, anticorps me, anticorps motheaten, anticorps Ptph6, anticorps Shp-1, anticorps fj22f05, anticorps wu:fj22f05, anticorps zgc:55501, anticorps ptpn6, anticorps protein tyrosine phosphatase, non-receptor type 6, anticorps protein tyrosine phosphatase, non-receptor type 6 L homeolog, anticorps PTPN6, anticorps Ptpn6, anticorps ptpn6, anticorps ptpn6.L

Sujet: The phosphorylation state of receptors and signal transduction molecules influences almost every cell activities. The phosphorylation rate is regulated by kinases which add phosphate group and by phosphatases which remove phosphate group form the amino acid residues on protein molecules. Protein tyrosine phosphatase 1 C (PTP1C) is a tyrosine phosphatase highly expressed in heomatopoietic cells. PTP1C was found to co-precipitate with B lymphocytespecific cell surface glycoprotein CD22, after anti-immunoglobulin stimulation. Study with PTP1C deficient mice showed that the phosphatase may implicate with negative selection in B cell immunity.Synonyms: HCP, Hematopoietic cell protein-tyrosine phosphatase, PTP-1C, PTP1C, PTPN-6, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6

ID gène: 5777

UniProt: P29350

Pathways: Signalistation JAK/STAT, TCR Signaling, Signalisation TLR, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling