IL-2 anticorps

N° du produit ABIN452490

Détail du produit anti-IL-2 anticorps

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-2 est non-conjugé

Application: Enzyme Immunoassay (EIA), ELISA (Capture)

Specificité: Reactive to the recombinant Human IL2.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: IL-2, TCGF, T-cell growth factor

Purification: Affinity Chromatography on Protein G

Immunogène: Recombinant Human Interleukin-2 (IL2)

Clone: 9F9

Isotype: IgG2a

Information d'application

Indications d'application: ELISA: Clone 9F9 can be used as Capture antibody to detect recombinant Human IL-2. Thisclone matches with HRP conjugated clone 5A8, clone 10C4 and clone 6B1. When used reversely as detection antibody, 9F9 also matches with 5A8, 10C5 and 6B1. However, clone 9F9 produced better results when it is used as Capture antibody.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with double distillated water is recommended to adjust the final concentration to 1.0 mg/mL

Concentration: 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Agent conservateur: Without preservative

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur IL-2

Antigène: IL-2 (IL2) (Interleukin 2 (IL2))

Autre désignation: Interleukin-2 / IL2 (IL2 Produits)

Synonymes: anticorps IL2, anticorps IL-2, anticorps il2, anticorps TCGF, anticorps lymphokine, anticorps Il-2, anticorps POIL2, anticorps interleukin 2, anticorps interleukin-15, anticorps IL2, anticorps il2, anticorps LOC100303688, anticorps Il2

Sujet: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. IL2 has been shown to have antitumor effects in some studies. This is probably mediated by cytotoxic effector cells.Synonyms: IL-2, T-cell growth factor, TCGF

ID gène: 3558

UniProt: P60568

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation