ABCD1 anticorps (Internal Region)

N° du produit ABIN452684

Détail du produit anti-ABCD1 anticorps

Antigène: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCD1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes ABCD1 (Internal).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence C-EDMQRKGYSEQD, from the internal region of the protein sequence according to NP_000024.2.

Information d'application

Indications d'application: Peptide ELISA: Antibody Detection Limit Dilution: 1/32000. Western Blot: Preliminary experiments gave an approx.50 kDa band in Human Brain(Cerebellum) lysates after 1 μg/mL antibody staining. Please note that currently we cannotfind an explanation in the literature for the band we observe given the calculated size of82.0 kDa according to NP_000024.2. The 50 kDa band was successfully blocked byincubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur ABCD1

Antigène: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Autre désignation: ABCD1 / ALDP (ABCD1 Produits)

Synonymes: anticorps ABC42, anticorps ALD, anticorps ALDP, anticorps AMN, anticorps RGD1562128, anticorps zgc:172102, anticorps ABCD1, anticorps Ald, anticorps Aldgh, anticorps ATP binding cassette subfamily D member 1, anticorps ATP-binding cassette, sub-family D (ALD), member 1, anticorps ATP-binding cassette sub-family D member 1, anticorps ATP binding cassette subfamily D member 1 L homeolog, anticorps ABCD1, anticorps Abcd1, anticorps abcd1, anticorps CpipJ_CPIJ013253, anticorps VDBG_05717, anticorps abcd1.L

Sujet: ABCD1 belongs to the ALD subfamily, of the superfamily of ATP-binding cassette (ABC) transporters and is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.Synonyms: ATP-binding cassette sub-family D member 1

ID gène: 215

NCBI Accession: NP_000024

UniProt: P33897

Pathways: Monocarboxylic Acid Catabolic Process