CBFB anticorps (Middle Region)
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- Antigène Voir toutes CBFB Anticorps
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBFB est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody detects CBFB at Center.
- Réactivité croisée (Details)
- Species reactivity (tested):Human
- Purification
- Purified through a protein A column, followed by peptide affinity purification
- Immunogène
- KLH conjugated synthetic peptide selected from the Center region of human CBFB
- Top Product
- Discover our top product CBFB Anticorps primaire
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- Indications d'application
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Western blot: 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS with 0.09 % (W/V) sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Antigène
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- Autre désignation
- CBFB (CBFB Produits)
- Synonymes
- anticorps PEBP2B, anticorps Cbfb, anticorps pebp2b, anticorps Pebp2, anticorps CBFB, anticorps unp1266, anticorps cbf-beta, anticorps cbfbeta, anticorps pea2-beta, anticorps pebp2-beta, anticorps AI893578, anticorps PEA2, anticorps PEBP2b, anticorps Pebpb2, anticorps core-binding factor beta subunit, anticorps core binding factor beta subunit, anticorps core-binding factor, beta subunit, anticorps core-binding factor, beta subunit S homeolog, anticorps core binding factor beta, anticorps CBFB, anticorps Cbfb, anticorps cbfb, anticorps cbfb.S
- Sujet
- CBFB is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit, it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters.Synonyms: CBF beta, CBF-beta, Core-binding factor beta, PEA2-beta, PEBP2-beta, Polyomavirus enhancer-binding protein 2 beta subunit, SL3-3 enhancer factor 1 subunit beta, SL3/AKV core-binding factor beta subunit
- Poids moléculaire
- 21508 Da
- ID gène
- 865
- NCBI Accession
- NP_001746
- UniProt
- Q13951
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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