PPAP2B anticorps

N° du produit ABIN4620345

Détail du produit anti-PPAP2B anticorps

Antigène: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPAP2B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to Phosphatidic Acid Phosphatase 2B .

Purification: Affinity Purified

Immunogène: Synthetic peptide derived from the phosphatidic acid phosphatase 2B protein

Isotype: IgG

Information d'application

Indications d'application: Western Blot. Enzyme Immunoassay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Ship on dry ice. Store (in aliquots) at -20 °C to -70 °C.

Détails sur PPAP2B

Antigène: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Autre désignation: PPAP2B / LPP3 (PPAP2B Produits)

Synonymes: anticorps Dri42, anticorps LPP3, anticorps PAP2B, anticorps VCIP, anticorps 1110003O22Rik, anticorps 2610002D05Rik, anticorps AV025606, anticorps D4Bwg0538e, anticorps D4Bwg1535e, anticorps Lpp3, anticorps Ppab2b, anticorps dri42, anticorps lpp3, anticorps pap2b, anticorps ppap2bb, anticorps vcip, anticorps ppap2b, anticorps ppap2ba, anticorps PPAP2B, anticorps si:dkey-19f4.1, anticorps phospholipid phosphatase 3, anticorps phospholipid phosphatase 3 L homeolog, anticorps phospholipid phosphatase 3 S homeolog, anticorps PLPP3, anticorps Plpp3, anticorps plpp3.L, anticorps plpp3.S, anticorps plpp3

Sujet: Vascular endothelial growth factor and type I collagen inducible protein (VCIP), also known as phosphatidic acid phosphatase 2b (PAP2b), was originally identified in a functional assay of angiogenesis. VCIP/PAP2b exhibits an Arg - Gly - Asp (RGD) cell adhesion sequence. Immunoprecipitation and fluorescence-activated cell sorting analyses demonstrated that VCIP-RGD is exposed to the outside of the cell surface. Retroviral transduction of VCIP can induce cell aggregation and cell-cell interactions, modestly increase p120 catenin expression and promote activation of the Fak, Akt and GSK3ß protein kinases. Expression of VCIP promoted adhesion, spreading and tyrosine phosphorylation of Fak, Shc, Cas and paxillin in endothelial cells. PAP2b/VCIP is expressed in close proximity to vascular endothelial growth factor, von Willebrand factor and {alpha}vbeta3 integrin in tumor vasculatures.Synonyms: Lipid phosphate phosphohydrolase 3, PAP2-beta, PAP2B, Phosphatidate phosphohydrolase type 2b, Phosphatidic acid phosphatase 2b, VCIP, Vascular endothelial growth factor and type I collagen-inducible protein

ID gène: 8613

NCBI Accession: NP_003704

UniProt: O14495