Lysine (K)-Specific Methyltransferase 2B (KMT2B) (AA 2703-2715) anticorps

N° du produit ABIN462281

Détail du produit

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Épitope: AA 2703-2715

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Singe, Porc, Poisson zèbre (Danio rerio)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human MLL4.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Pig, Zebrafish (100%) Xenopus, Pufferfish (92%) Chimpanzee, Elephant, Panda, Dog, Bat, Horse, Opossum, Turkey, Chicken (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide CNCGAKRCRRFLN from the C-terminus of human MLL4 (NP_055542.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Pig, Zebrafish (100%), Xenopus, Pufferfish (92%), Chimpanzee, Elephant, Panda, Dog, Bat, Horse, Opossum, Turkey, Chicken (85%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:128000)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détail du antigène

Antigène: Lysine (K)-Specific Methyltransferase 2B (KMT2B)

Autre désignation: KMT2B / MLL4 (KMT2B Produits)

Synonymes: anticorps HRX2, anticorps MLL1B, anticorps MLL2, anticorps MLL4, anticorps TRX2, anticorps WBP7, anticorps lysine methyltransferase 2B, anticorps KMT2B

Sujet: Name/Gene ID: KMT2B

Synonyms: KMT2B, Lysine N-methyltransferase 2D, MLL4, HRX2, KMT2D, WBP-7, WW domain binding protein 7, Trithorax homologue 2, WBP7, KIAA0304, Lysine N-methyltransferase 2B, Trithorax homolog 2, TRX2, WW domain-binding protein 7

ID gène: 9757

NCBI Accession: NP_055542

UniProt: Q9UMN6

Pathways: L'effet Warburg