GRIA4 anticorps (AA 279-292)

N° du produit ABIN462292

Détail du produit anti-GRIA4 anticorps

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Épitope: AA 279-292

Reactivité: Humain, Souris, Rat, Poulet, Singe, Boeuf (Vache), Roussette (Chauve-souris), Chien, Cheval, Lapin

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marque: IHC-plus™

Specificité: Human GRIA4 / GLUR4. This antibody is expected to recognize all reported isforms (NP_000820.3, NP_001070711.1, NP_001070712.1). Reported variants NP_001070712.1 and NP_001106283.1 represent identical protein.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus (100%) Lizard (93%) Xenopus, Stickleback, Pufferfish, Zebrafish, Trachemys (86%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-KKLDQREYPGSETP from an internal region of human GRIA4 / GLUR4 (NP_000820.3, NP_001070711.1, NP_001070712.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Opossum, Turkey, Chicken, Platypus (100%), Lizard (93%), Xenopus, Stickleback, Pufferfish, Zebrafish, Trachemys (86%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:128000, 0.3 - 1 μg/mL), WB (0.3 - 1 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. Peptide ELISA: antibody detection limit dilution 1:128000. Western Blot: Approx. 90 kD band observed in Human Brain (Cerebellum) lysates (calculated MW of 99.2 kD according to NP_001070711.1). Recommended concentration: 0.3-1 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur GRIA4

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Autre désignation: GRIA4 / GLUR4 (GRIA4 Produits)

Synonymes: anticorps GLUR4, anticorps GLUR4C, anticorps GLURD, anticorps GluA4, anticorps GluR4, anticorps GluR4d, anticorps GLUR4/D, anticorps glur4, anticorps GluR-D, anticorps Glur-4, anticorps Glur4, anticorps Gluralpha4, anticorps spkw1, anticorps DKFZp459P0616, anticorps glur4a, anticorps gria4, anticorps iGluR4, anticorps ZfGluR4b, anticorps fj46g06, anticorps glur4b, anticorps wu:fj46g06, anticorps glutamate ionotropic receptor AMPA type subunit 4, anticorps glutamate receptor, ionotropic, AMPA 4, anticorps glutamate receptor, ionotropic, AMPA4 (alpha 4), anticorps glutamate receptor, ionotropic, AMPA 4a, anticorps glutamate receptor, ionotropic, AMPA 4b, anticorps GRIA4, anticorps gria4, anticorps Gria4, anticorps gria4a, anticorps gria4b

Sujet: Name/Gene ID: GRIA4
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIA4, GluA4, GluR-4, GLUR4, GLUR4C, Glutamate receptor type d, GluR-D, GLURD, Glutamate receptor 4

ID gène: 2893

NCBI Accession: NP_000820, NP_001070711, NP_001070712

UniProt: P48058

Pathways: Signalisation PI3K-Akt