DcR2 anticorps (N-Term) (PE)

N° du produit ABIN487317

Détail du produit anti-DcR2 anticorps (PE)

Antigène: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Épitope: AA 1-210, N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DcR2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: The antibody TRAIL-R4-01 reacts with TRAIL-R4, a 42 kDa transmembrane protein expressed on various blood cells.

Réactivité croisée (Details): Species reactivity (tested):Human.

Attributs du produit: Synonyms: TNFRSF10D, DCR2, TRAIL-R4, TRUNDD, Decoy receptor 2, TRAIL receptor 4, Tumor necrosisfactor receptor superfamily member 10D, TNF-related apoptosis-inducing ligand receptor 4,TRAIL receptor with a truncated death domain

Purification: Size-Exclusion Chromatography.

Immunogène: TRAIL-R4 (aa 1-210) - hIgGhc fusion protein

Clone: TRAIL-R4-01

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS containing 15 mM Sdium Azide as preservative and 0.2 % (w/v) high-grade (Protease free) BSA as a stabilizing agent.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid prolonged exposure to light.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur DcR2

Antigène: DcR2 (TNFRSF10D) (Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain (TNFRSF10D))

Autre désignation: CD264 / TRAILR4 (TNFRSF10D Produits)

Synonymes: anticorps TNFRSF10D, anticorps CD264, anticorps DCR2, anticorps TRAIL-R4, anticorps TRAILR4, anticorps TRUNDD, anticorps TNF receptor superfamily member 10d, anticorps tumor necrosis factor receptor superfamily member 10D, anticorps TNFRSF10D, anticorps LOC716901

Sujet: TRAIL-R4 (CD264, TR4, DcR2, TRUNDD), expressed mainly on CD8+ and NK cells, belongs to receptors of TRAIL, a TNF-like membrane toxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R4, however, contains partially truncated death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by impairment death-inducing signaling complex (DISC) processing. TRAIL-R4 interacts with death receptor 5 (DR5) in the native DISC in a TRAIL-dependent manner and prevents its corecruitment with death receptor 4 (DR4).Synonyms: DCR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRAIL-R4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D

ID gène: 8793

UniProt: Q9UBN6

Pathways: Apoptose