2B4 anticorps (Internal Region, pTyr271)
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- Antigène Voir toutes 2B4 (CD244) Anticorps
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
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Épitope
- Internal Region, pTyr271
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Reactivité
- Humain
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Hôte
- Chèvre
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp 2B4 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)
- Séquence
- c-EFLTIPYEDV KD
- Specificité
- This antibody recognizes CD244.
- Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
- Immunogène
- Peptide with sequence from the internal region of the protein sequence according to NP_057466.1.
- Top Product
- Discover our top product CD244 Anticorps primaire
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- Indications d'application
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Peptide ELISA: 1/64000. Western blot: Approx 75 kDa band observed in Human Natural Killer (NK) cell lysates afterimmunoprecipitation with mouse monoclonal antibody C1.7 coupled to Protein G agarose(calculated MW of 41.5 kDa according to NP_057466.1). We do note that CD244 is aglycoprotein which makes a higher size band to be expected. Recommended concentration: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Antigène
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
- Autre désignation
- CD244 (CD244 Produits)
- Synonymes
- anticorps CD244, anticorps 2B4, anticorps NAIL, anticorps NKR2B4, anticorps Nmrk, anticorps SLAMF4, anticorps C9.1, anticorps F730046O15Rik, anticorps Ly90, anticorps CD244 molecule, anticorps CD244 natural killer cell receptor 2B4, anticorps CD244, anticorps Cd244
- Sujet
- CD244 is expressed on all human NK cells, a subpopulation of T cells, basophils and monocytes. CD244 activates NK cell mediated cytotoxicity, induces secretion of IFN-gamma and matrix metalloproteinases, and NK cell invasiveness. Although there have been several molecules shown to interact with CD244, the signaling mechanism ofCD244-mediated activation of NK cells is still unknown. It is a high affinity receptor for CD48.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4
- ID gène
- 51744
- NCBI Accession
- NP_057466
- UniProt
- Q9BZW8
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