ERCC6 anticorps (N-Term)

N° du produit ABIN4886573

Détail du produit anti-ERCC6 anticorps

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Épitope: AA 160-205, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC6 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for DNA excision repair protein ERCC-6(ERCC6) detection. Tested with WB in Human,Rat.

Séquence: QAATSRDINR KLDSVKRQKY NKEQQLKKIT AKQKHLQAIL GGAEVK

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for DNA excision repair protein ERCC-6(ERCC6) detection. Tested with WB in Human,Rat.
Gene Name: ERCC excision repair 6, chromatin remodeling factor
Protein Name: DNA excision repair protein ERCC-6

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human CSB (160-205aa QAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVK).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ERCC6

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Autre désignation: ERCC6 (ERCC6 Produits)

Synonymes: anticorps ARMD5, anticorps CKN2, anticorps COFS, anticorps COFS1, anticorps CSB, anticorps RAD26, anticorps UVSS1, anticorps 4732403I04, anticorps C130058G22Rik, anticorps ercc6, anticorps Ercc6, anticorps ERCC excision repair 6, chromatin remodeling factor, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 6, anticorps excision repair cross-complementation group 6, anticorps DNA excision repair protein ERCC-6, anticorps ERCC6, anticorps Ercc6, anticorps ercc6, anticorps LOC100719487

Sujet: DNA excision repair protein ERCC-6 (also CS-B protein) is a protein that in humans is encoded by the ERCC6 gene. This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

Synonyms: ARMD 5 | ARMD5 | CKN 2 | CKN2 | COFS | COFS1 | CSB | ERCC 6 | ERCC6 | RAD26 | UVSS1 | Q03468

ID gène: 2074

UniProt: Q03468

Pathways: Réparation de l'ADN, Chromatin Binding