SLC1A3 anticorps (N-Term)
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- Antigène Voir toutes SLC1A3 Anticorps
- SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))
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Épitope
- AA 14-42, N-Term
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLC1A3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 1(SLC1A3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Séquence
- RMERFQQGVR KRTLLAKKKV QNITKEDVK
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 1(SLC1A3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
Protein Name: Excitatory amino acid transporter 1 - Purification
- Immunogen affinity purified.
- Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of human EAAT1 (14-42aa RMERFQQGVRKRTLLAKKKVQNITKEDVK), different from the related mouse sequence by three amino acids, and identical to the related rat sequence.
- Isotype
- IgG
- Top Product
- Discover our top product SLC1A3 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." dans: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, (2014) (PubMed).
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Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." dans: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, (2014) (PubMed).
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- Antigène
- SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))
- Autre désignation
- SLC1A3 (SLC1A3 Produits)
- Synonymes
- anticorps AF001784, anticorps CG3747, anticorps Dglt-1, anticorps Dglut-1, anticorps Dmel\\CG3747, anticorps EAAT, anticorps EAAT1, anticorps dEAAT, anticorps dEAAT1, anticorps dEaat1, anticorps slc1a3, anticorps wu:fb98e05, anticorps wu:fd50b05, anticorps zgc:56661, anticorps zgc:77768, anticorps SLC1A3, anticorps GLAST, anticorps GluT-1, anticorps EA6, anticorps GLAST1, anticorps AI504299, anticorps B430115D02Rik, anticorps Eaat1, anticorps GLAST-1, anticorps GLU-T, anticorps Gmt1, anticorps MGluT1, anticorps Excitatory amino acid transporter 1, anticorps solute carrier family 1 member 3, anticorps excitatory amino acid transporter 1, anticorps solute carrier family 1 (glial high affinity glutamate transporter), member 3a, anticorps solute carrier family 1 (glial high affinity glutamate transporter), member 3, anticorps Eaat1, anticorps SLC1A3, anticorps PTRG_00379, anticorps Tsp_02392, anticorps slc1a3a, anticorps Slc1a3
- Sujet
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Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. It is mapped to chromosome 5p13.2 by fluorescence in situ hybridization (FISH). And this gene transports L-glutamate and also L- and D-aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Furthermore, this gene acts as a symport by cotransporting sodium.
Synonyms: EA6 | EAA1 | EAAT 1 | EAAT1 | EAAT1 | GLAST | GLAST1 | Glast | GLAST-1 | SLC1A3 | P43003 - ID gène
- 6507
- UniProt
- P43003
- Pathways
- Sensory Perception of Sound, Synaptic Membrane, Dicarboxylic Acid Transport
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