ALIX anticorps

N° du produit ABIN4915785

Détail du produit anti-ALIX anticorps

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ALIX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Reacts with human ALIX protein

Purification: Purified (protein A)

Immunogène: Purified recombinant human ALIX protein

Clone: 8E8

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB(1:200 - 1:1000) IHC(1:100 - 1:500)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur ALIX

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Autre désignation: ALIX (PDCD6IP Produits)

Synonymes: anticorps DDBDRAFT_0167145, anticorps DDBDRAFT_0185177, anticorps DDB_0167145, anticorps DDB_0185177, anticorps AIP1, anticorps ALIX, anticorps DRIP4, anticorps HP95, anticorps AI480591, anticorps AW544830, anticorps Aip1, anticorps Alix, anticorps C76364, anticorps Eig2, anticorps mKIAA1375, anticorps CG12876, anticorps DAIP1, anticorps Dmel\\CG12876, anticorps GB11744, anticorps RGD1561176, anticorps zgc:63638, anticorps wu:fb70d03, anticorps wu:fy65h02, anticorps PDCD6IP, anticorps aip1, anticorps alix, anticorps hp95, anticorps drip4, anticorps ALG-2 interacting protein X, anticorps programmed cell death 6 interacting protein, anticorps programmed cell death 6-interacting protein, anticorps Programmed cell death 6 interacting protein, anticorps programmed cell death 6 interacting protein L homeolog, anticorps alxA, anticorps PDCD6IP, anticorps Pdcd6ip, anticorps ALiX, anticorps LOC412662, anticorps pdcd6ip, anticorps Bm1_48390, anticorps pdcd6ip.L

Sujet: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses).

ID gène: 10015

UniProt: Q8WUM4

Pathways: Signalisation p53, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation