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AGT anticorps (N-Term)

AGT Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4888984
  • Antigène Voir toutes AGT Anticorps
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    Épitope
    • 16
    • 15
    • 13
    • 8
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 118
    • 55
    • 53
    • 7
    • 2
    • 2
    • 2
    • 1
    Humain
    Hôte
    • 104
    • 35
    • 1
    Lapin
    Clonalité
    • 99
    • 41
    Polyclonal
    Conjugué
    • 70
    • 19
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AGT est non-conjugé
    Application
    • 109
    • 46
    • 36
    • 27
    • 27
    • 18
    • 14
    • 13
    • 9
    • 7
    • 7
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Specificité
    Reacts with human 53 kDa AGT protein
     Réactivité croisée
    Souris, Rat (Rattus)
    Réactivité croisée (Details)
    Cross reacts with the proteins from mouse, rat and other species due to sequence homology.
    Purification
    Purified (protein A)
    Immunogène
    Synthetic peptide derived from Nter domain of human Serpin A8 protein
    Top Product
    Discover our top product AGT Anticorps primaire
  • Indications d'application

    Working dilution: Optimal dilution should be determined by the end user The following are guidelines only :
    - IHC : 1/50 to 1/500 - WB : 1/200 to 1/2 000

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Must be reconstituted in distilled water.
    Buffer
    Tris 0,1M, glycine 0,1M, sucrose 2 %
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    Date de péremption
    24 months
  • Antigène
    AGT (Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
    Autre désignation
    Angiotensinogen (AGT) (AGT Produits)
    Synonymes
    anticorps ANHU, anticorps SERPINA8, anticorps AI265500, anticorps AngI, anticorps AngII, anticorps Aogen, anticorps Serpina8, anticorps ANRT, anticorps Ang, anticorps PAT, anticorps wu:fb62f06, anticorps wu:fj87b02, anticorps zgc:111892, anticorps AGT, anticorps angt, anticorps ANGT, anticorps angiotensinogen, anticorps angiotensinogen (serpin peptidase inhibitor, clade A, member 8), anticorps AGT, anticorps Agt, anticorps agt
    Sujet
    Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. In response to lowered blood pressure, the enzyme renin cleaves angiotensinogen to produce angiotensin-1 (angiotensin 1-10). Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2 (angiotensin 1-8). Angiotensin-1 and angiotensin-2 can be further processed to generate angiotensin-3 (angiotensin 2-8), angiotensin-4 (angiotensin 3-8). Angiotensin 1-7 is cleaved from angiotensin-2 by ACE2 or from angiotensin-1 by MME (neprilysin). Angiotensin 1-9 is cleaved from angiotensin-1 by ACE2.
    UniProt
    P01019
    Pathways
    Signalistation JAK/STAT, ACE Inhibitor Pathway, EGFR Signaling Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Feeding Behaviour, Monocarboxylic Acid Catabolic Process, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Regulation of long-term Neuronal Synaptic Plasticity
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