p53 anticorps
-
- Antigène Voir toutes p53 (TP53) Anticorps
- p53 (TP53) (Tumor Protein P53 (TP53))
-
Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Cet anticorp p53 est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Specificité
- Reacts with human truncated p53 from MCF7 cells and endogenous p53 from various tumour cells
- Purification
- Purified (protein A)
- Immunogène
- Recombinant 6-histidine-troncated p53(6H-Cp53)
- Clone
- H53C2
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TP53 Anticorps primaire
-
-
- Indications d'application
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC(1:100 - 1:500) IP (1:50 - 1:200) WB(1:200 - 1:1000) - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Concentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Date de péremption
- 24 months
-
- Antigène
- p53 (TP53) (Tumor Protein P53 (TP53))
- Autre désignation
- Cellular Tumor Antigen p53 (TP53 Produits)
- Synonymes
- anticorps BCC7, anticorps LFS1, anticorps P53, anticorps TRP53, anticorps p53, anticorps Trp53, anticorps brp53, anticorps drp53, anticorps etID22686.5, anticorps fb40d06, anticorps wu:fb40d06, anticorps zgc:111919, anticorps Tp53, anticorps bbl, anticorps bfy, anticorps bhy, anticorps p44, anticorps tp53, anticorps Xp53, anticorps TP53, anticorps tumor protein p53, anticorps cellular tumor antigen p53, anticorps transformation related protein 53, anticorps tumor protein p53 L homeolog, anticorps TP53, anticorps CpipJ_CPIJ002758, anticorps Tp53, anticorps tp53, anticorps Trp53, anticorps tp53.L
- Sujet
- Belongs to the p53 family. Acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis, the function is largely independent of transcription.
- ID gène
- 7157
- UniProt
- P04637
- Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
-