UNC5B anticorps

N° du produit ABIN4889372

Détail du produit anti-UNC5B anticorps

Antigène: UNC5B (Netrin receptor UNC5B (UNC5B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UNC5B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Reacts with human, mouse, rat UNC5B

Purification: Purified (protein A)

Immunogène: UNC5B human recombinant protein

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:5000) IHC(1:100 - 1:500)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water to reach 1 mg/mL

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur UNC5B

Antigène: UNC5B (Netrin receptor UNC5B (UNC5B))

Autre désignation: Netrin Receptor UNC5B (UNC5B Produits)

Synonymes: anticorps unc5h2, anticorps 6330415E02Rik, anticorps A630020F16, anticorps D10Bwg0792e, anticorps Unc5h2, anticorps UNC5H2, anticorps p53RDL1, anticorps UNC5C, anticorps UNC5B, anticorps p53rdl1, anticorps unc-5 netrin receptor B, anticorps unc-5 netrin receptor B L homeolog, anticorps unc5b, anticorps Unc5b, anticorps UNC5B, anticorps unc5b.L

Sujet: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Mediates apoptosis by activating DAPK1. In the absence of NTN1, activates DAPK1 by reducing its autoinhibitory phosphorylation at Ser-308 thereby increasing its catalytic activity

UniProt: Q8IZJ1