COL4a3 anticorps

N° du produit ABIN4902585

Détail du produit anti-COL4a3 anticorps

Antigène: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp COL4a3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Séquence: RGPTEYYDTY QEK

Purification: Anti-COL4A3 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. According to PubMed:8083201, alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. According to PubMed:7523402, alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3. Isoform 1 and isoform 3 are expressed at low levels in artery, fat, pericardium and peripherical nerve, but not in placenta, mesangium, skin, pleura and cultured umbilical endothelial cells.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in Tris saline, with 0.5 % bovine serum albumin and 0.02 % sodium azide,  pH 7.3 .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur COL4a3

Antigène: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Autre désignation: COL4A3 (COL4A3 Produits)

Synonymes: anticorps zTumstatin, anticorps [a]3(IV), anticorps alpha3(IV), anticorps collagen type IV alpha 3 chain, anticorps collagen, type IV, alpha 3, anticorps COL4A3, anticorps col4a3, anticorps Col4a3

Sujet: Goat polyclonal to COL4A3.

ID gène: 1285

UniProt: Q01955

Pathways: Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity