FCAR anticorps

N° du produit ABIN4903651

Détail du produit anti-FCAR anticorps

Antigène: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCAR est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: A synthetic Peptide of human FCAR

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:1000

Commentaires:

Isoform A,1, isoform A,2 and isoform A,3 are differentially expressed between blood and mucosal myeloid cells, Isoform A,1, isoform A,2 and isoform A,3 are expressed in monocytes, Isoform A,1 and isoform A,2 are expressed in alveolar macrophages

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20C. Avoid freeze / thaw cycles.

Détails sur FCAR

Antigène: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Autre désignation: FCAR (FCAR Produits)

Synonymes: anticorps CD89, anticorps Fc fragment of IgA receptor, anticorps Fc fragment of IgA, receptor for, anticorps FCAR

Sujet: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 32.265 kDa

ID gène: 2204

UniProt: P24071