ABCC8 anticorps (AA 1559-1571)

N° du produit ABIN490470

Détail du produit anti-ABCC8 anticorps

Antigène: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Épitope: AA 1559-1571

Reactivité: Humain, Chien, Boeuf (Vache), Cheval

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC8 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Human ABCC8 / MRP8.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda, Bovine, Dog, Horse (100%) Marmoset, Mouse, Rat, Bat, Rabbit, Pig (92%) Hamster (85%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-EFDKPEKLLSRKD from the C-terminus of human ABCC8 / MRP8 (NP_000343.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Elephant, Panda, Bovine, Dog, Horse (100%), Marmoset, Mouse, Rat, Bat, Rabbit, Pig (92%), Hamster (85%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: Peptide-ELISA (1:8000), WB (0.5 - 1.5 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 170  kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 177  kDa according to NP_000343.2). Recommended concentration: 0.5-1.5 μg/mL. An additional band of unknown identity was also consistently observed at 23  kDa. This band was successfully blocked by incubation with the immunising peptide.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur ABCC8

Antigène: ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))

Autre désignation: ABCC8 / SUR1 (ABCC8 Produits)

Synonymes: anticorps ABC36, anticorps HHF1, anticorps HI, anticorps HRINS, anticorps MRP8, anticorps PHHI, anticorps SUR, anticorps SUR1, anticorps SUR1delta2, anticorps TNDM2, anticorps D930031B21Rik, anticorps Sur, anticorps Sur1, anticorps ATP binding cassette subfamily C member 8, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 8, anticorps ABCC8, anticorps Abcc8

Sujet: Name/Gene ID: ABCC8
Subfamily: ATP-binding cassette - ABCC/MRP
Family: Transporter

Synonyms: ABCC8, ABC36, HI, PHHI, Sulfonylurea receptor, SUR, Sulfonylurea receptor 1, MRP8, SUR1delta2, HHF1, HRINS, SUR1, TNDM2

ID gène: 6833

NCBI Accession: NP_000343

UniProt: Q09428

Pathways: Negative Regulation of Hormone Secretion