PCSK2 anticorps

N° du produit ABIN4904707

Détail du produit anti-PCSK2 anticorps

Antigène: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCSK2 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The protein undergoes an initial autocatalytic processing event and interacts with a neuroendocrine secretory protein in the ER, exits the ER and sorts to secretory granules, where it is cleaved and catalytically activated during intracellular transport. The encoded protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2014]

Purification: Affinity purification

Immunogène: Recombinant protein of human PCSK2.

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur PCSK2

Antigène: PCSK2 (Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2))

Autre désignation: PCSK2 (PCSK2 Produits)

Synonymes: anticorps NEC 2, anticorps NEC-2, anticorps NEC2, anticorps PC2, anticorps SPC2, anticorps PCSK2, anticorps 6330411F23Rik, anticorps AI839700, anticorps Nec-2, anticorps Nec2, anticorps Phpp-2, anticorps pc2, anticorps nec2, anticorps spc2, anticorps pcsk2, anticorps pcsk2-A, anticorps proprotein convertase subtilisin/kexin type 2, anticorps proprotein convertase subtilisin/kexin type 2 L homeolog, anticorps PCSK2, anticorps pcsk2, anticorps Pcsk2, anticorps pcsk2.L

ID gène: 5126

UniProt: P16519

Pathways: Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity