TGFBR3 anticorps

N° du produit ABIN4905408

Détail du produit anti-TGFBR3 anticorps

Antigène: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFBR3 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Transforming growth factor-β (TGF-β) superfamily members are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis (1-4). TGF-β elicits signaling through three cell surface receptors: type I (RI), type II (RII), and type III (RIII). Type I and type II receptors are serine/threonine kinases that form a heteromeric complex. In response to ligand binding, the type II receptors form a stable complex with the type I receptors allowing phosphorylation and activation of type I receptor kinases (5). The type III receptor, also known as betaglycan, is a transmembrane proteoglycan with a large extracellular domain that binds TGF-β with high affinity but lacks a cytoplasmic signaling domain (6,7). Expression of the type III receptor can regulate TGF-β signaling through presentation of the ligand to the signaling complex. The only known direct TGF-β signaling effectors are the Smad family proteins, which transduce signals from the cell surface directly to the nucleus to regulate target gene transcription (8,9).

Purification: Affinity purification

Immunogène: Recombinant protein of human TGFBR3.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur TGFBR3

Antigène: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Autre désignation: TGFBR3 (TGFBR3 Produits)

Synonymes: anticorps TGFBR3, anticorps DKFZp469I0915, anticorps BGCAN, anticorps betaglycan, anticorps 1110036H20Rik, anticorps AU015626, anticorps AW215636, anticorps TBRIII, anticorps transforming growth factor beta receptor 3, anticorps transforming growth factor, beta receptor III, anticorps TGFBR3, anticorps tgfbr3, anticorps Tgfbr3

ID gène: 7049

UniProt: Q03167