AFG3L2 anticorps
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- Antigène Voir toutes AFG3L2 Anticorps
- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp AFG3L2 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Antigen affinity
- Immunogène
- Amino acids R168-D250 of the human protein were used as the immunogen for the AFG3L2 antibody.
- Isotype
- IgG
- Top Product
- Discover our top product AFG3L2 Anticorps primaire
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- Indications d'application
- Optimal dilution of the AFG3L2 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
- Restrictions
- For Research Use only
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Stock
- -20 °C
- Stockage commentaire
- After reconstitution, the AFG3L2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Antigène
- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
- Autre désignation
- AFG3L2 (AFG3L2 Produits)
- Synonymes
- anticorps MGC147390, anticorps si:ch211-12e1.4, anticorps SCA28, anticorps SPAX5, anticorps 2310036I02Rik, anticorps AW260507, anticorps Emv66, anticorps par, anticorps AFG3 like matrix AAA peptidase subunit 2, anticorps AFG3-like protein 2, anticorps AFG3 ATPase family gene 3-like 2 (S. cerevisiae), anticorps AFG3-like AAA ATPase 2, anticorps AFG3-like AAA ATPase 2 L homeolog, anticorps AFG3L2, anticorps LOC578526, anticorps afg3l2, anticorps afg3l2.L, anticorps Afg3l2
- Sujet
- AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.
- UniProt
- Q9Y4W6
- Pathways
- Skeletal Muscle Fiber Development
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