KIAA1524 anticorps

N° du produit ABIN4950567

Détail du produit anti-KIAA1524 anticorps

Antigène: KIAA1524

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIAA1524 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids EVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH of human KIAA1524 were used as the immunogen for the CIP2A antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CIP2A antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CIP2A antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur KIAA1524

Antigène: KIAA1524

Autre désignation: CIP2A / KIAA1524 (KIAA1524 Produits)

Synonymes: anticorps CIP2A, anticorps p90, anticorps AA408511, anticorps AU018569, anticorps Cip2a, anticorps Kiaa1524, anticorps KIAA1524, anticorps LOC100222895, anticorps RGD1310335, anticorps cell proliferation regulating inhibitor of protein phosphatase 2A, anticorps RIKEN cDNA C330027C09 gene, anticorps KIAA1524, anticorps cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog, anticorps CONSTANS interacting protein 2a, anticorps CIP2A, anticorps C330027C09Rik, anticorps KIAA1524, anticorps cip2a.L, anticorps CIP2a, anticorps cip2a, anticorps Cip2a

Sujet: Protein CIP2A, also known as 'cancerous inhibitor of PP2A' and p90, is a protein that in humans is encoded by the KIAA1524 gene. It is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.

UniProt: Q8TCG1