GIP anticorps (Gastric Inhibitory Polypeptide)

Details for Product anti-GIP Antibody No. ABIN4951171
Antigène
  • GIP
  • xgip
  • Gludins
  • RATGLUDINS
  • gastric inhibitory polypeptide
  • gastric inhibitory polypeptide L homeolog
  • GIP
  • gip
  • Gip
  • gip.L
Reactivité
Humain
76
40
36
9
2
1
Hôte
Lapin
80
14
Clonalité
Polyclonal
Conjugué
Cet anticorp GIP est non-conjugé
5
3
3
3
3
3
3
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
45
44
26
13
12
10
10
9
6
6
3
3
3
1
1
1
1
Options
Immunogène Amino acids Y52-Q93 from the human protein were used as the immunogen for the GIP antibody.
Isotype IgG
Purification Antigen affinity
Plasmids, Primers & others Plasmids, Primers & others GIP products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation GIP / Gastric inhibitory polypeptide (GIP Antibody Extrait)
Sujet Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide, is an inhibiting hormone of the secretin family of hormones. GIP is thought to have significant effects on fatty acid metabolism through stimulation of lipoprotein lipase activity in adipocytes. Additionally, GIP release has been demonstrated in the ruminant animal and may play a role in nutrient partitioning in milk production (lipid metabolism). Recently, GIP appeared as a major player in bone remodelling. It was evidenced that genetic ablation of the GIP receptor in mice resulted in profound alterations of bone microarchitecture through modification of the adipokine network. Furthermore, the deficiency in GIP receptors has also been associated in mice with a dramatic decrease in bone quality and a subsequent increase in fracture risk.
UniProt P09681
Pathways Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
Indications d'application Optimal dilution of the GIP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL
Restrictions For Research Use only
Buffer 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Stock -20 °C
Stockage commentaire After reconstitution, the GIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Images (Fournisseur)
Image no. 1 for anti-Gastric Inhibitory Polypeptide (GIP) antibody (ABIN4951171) Western blot testing of human MCF7 cell lysate with GIP antibody. Expected molecular ...
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