GIP anticorps

N° du produit ABIN4951171

Détail du produit anti-GIP anticorps

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GIP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Amino acids Y52-Q93 from the human protein were used as the immunogen for the GIP antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the GIP antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the GIP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur GIP

Antigène: GIP (Gastric Inhibitory Polypeptide (GIP))

Autre désignation: GIP / Gastric inhibitory polypeptide (GIP Produits)

Synonymes: anticorps GIP, anticorps xgip, anticorps Gludins, anticorps RATGLUDINS, anticorps gastric inhibitory polypeptide, anticorps gastric inhibitory polypeptide L homeolog, anticorps GIP, anticorps gip, anticorps Gip, anticorps gip.L

Sujet: Gastric inhibitory polypeptide (GIP), also known as the glucose-dependent insulinotropic peptide, is an inhibiting hormone of the secretin family of hormones. GIP is thought to have significant effects on fatty acid metabolism through stimulation of lipoprotein lipase activity in adipocytes. Additionally, GIP release has been demonstrated in the ruminant animal and may play a role in nutrient partitioning in milk production (lipid metabolism). Recently, GIP appeared as a major player in bone remodelling. It was evidenced that genetic ablation of the GIP receptor in mice resulted in profound alterations of bone microarchitecture through modification of the adipokine network. Furthermore, the deficiency in GIP receptors has also been associated in mice with a dramatic decrease in bone quality and a subsequent increase in fracture risk.

UniProt: P09681

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism