NRIP1 anticorps

N° du produit ABIN4952410

Détail du produit anti-NRIP1 anticorps

Antigène: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRIP1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Amino acids EAHLQQYSREHALKTQNANQAASERLAAMARLQE of human RIP140/NRIP1 were used as the immunogen for the RIP140 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the RIP140 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the RIP140 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur NRIP1

Antigène: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Autre désignation: RIP140 / NRIP1 (NRIP1 Produits)

Synonymes: anticorps MGC68665, anticorps NRIP1, anticorps RIP140, anticorps 6030458L20Rik, anticorps 8430438I05Rik, anticorps 9630050P12, anticorps AA959574, anticorps AW456757, anticorps nuclear receptor interacting protein 1 S homeolog, anticorps nuclear receptor interacting protein 1, anticorps circumsporozoite protein, anticorps nrip1.S, anticorps NRIP1, anticorps nrip1, anticorps Nrip1, anticorps LOC100627733

Sujet: Nuclear receptor-interacting protein 1 (NRIP1), also known as receptor-interacting protein 140 (RIP140), is a protein that in humans is encoded by the NRIP1 gene. It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, including the estrogen receptor. RIP140 has an important role in regulating lipid and glucose metabolism, and regulates gene expression in metabolic tissues including heart, skeletal muscle, and liver. A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, including uncoupling protein 1 and carnitine palmitoyltransferase 1b.

UniProt: P48552

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway