CHEK1 anticorps (AA 258-287)
Aperçu rapide pour CHEK1 anticorps (AA 258-287) (ABIN3030468)
Antigène
Voir toutes CHEK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 258-287
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Fonction
- CHK1 Antibody
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Purification
- Antigen affinity
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Immunogène
- A portion of amino acids 258-287 from the human protein was used as the immunogen for this CHK1 antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the CHK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4oC for up to one month. For long term, aliquot the CHK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Autre désignation
- CHK1
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Sujet
- Checkpoint kinase 1, commonly referred to as CHK1 is an serine/threonine-specific protein kinase that in humans, is encoded by the CHEK1 gene. CHK1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death to prevent damaged cells from progressing through the cell cycle.
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UniProt
- O14757
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Pathways
- Signalisation p53, Apoptose, Cycle Cellulaire, Réparation de l'ADN
Antigène
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