ACVR1 anticorps (AA 132-162)

N° du produit ABIN3029855

Détail du produit anti-ACVR1 anticorps

Antigène: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Épitope: AA 132-162

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACVR1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat, Bovine

Purification: Purified

Immunogène: A portion of amino acids 132-162 from the human protein was used as the immunogen for this ALK2 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the ALK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the ALK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur ACVR1

Antigène: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Autre désignation: ALK2 (ACRV1 Produits)

Synonymes: anticorps ACTRI, anticorps ACVR1A, anticorps ACVRLK2, anticorps ALK2, anticorps FOP, anticorps SKR1, anticorps TSRI, anticorps ActR-IA, anticorps ActR-I, anticorps ActRIA, anticorps Acvr, anticorps Acvrlk2, anticorps Alk-2, anticorps Alk8, anticorps D330013D15Rik, anticorps Tsk7L, anticorps actri, anticorps acvr1, anticorps acvr1-a, anticorps acvr1-b, anticorps acvr1a, anticorps acvrlk2, anticorps alk-2, anticorps alk2, anticorps alk8, anticorps fop, anticorps sax, anticorps skr1, anticorps tsri, anticorps xALK-2, anticorps activin A receptor type 1, anticorps activin A receptor, type 1, anticorps activin A receptor type 1 S homeolog, anticorps ACVR1, anticorps Acvr1, anticorps acvr1.S

Sujet: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 (activin A type I receptor) signals a particular transcriptional response in concert with activin type II receptors.

UniProt: Q04771