ACVR1 anticorps (AA 21-120)
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- Antigène Voir toutes ACVR1 (ACRV1) Anticorps
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
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Épitope
- AA 21-120
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ACVR1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purification
- purified
- Immunogène
- Purified recombinant fragment of human ACVR1 (AA: 21-120) expressed in E. coli.
- Clone
- 2C1E8
- Isotype
- IgG1
- Top Product
- Discover our top product ACRV1 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM: 1:200 - 1:400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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- Antigène
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
- Autre désignation
- ACVR1 (ACRV1 Produits)
- Synonymes
- anticorps ACTRI, anticorps ACVR1A, anticorps ACVRLK2, anticorps ALK2, anticorps FOP, anticorps SKR1, anticorps TSRI, anticorps ActR-IA, anticorps ActR-I, anticorps ActRIA, anticorps Acvr, anticorps Acvrlk2, anticorps Alk-2, anticorps Alk8, anticorps D330013D15Rik, anticorps Tsk7L, anticorps actri, anticorps acvr1, anticorps acvr1-a, anticorps acvr1-b, anticorps acvr1a, anticorps acvrlk2, anticorps alk-2, anticorps alk2, anticorps alk8, anticorps fop, anticorps sax, anticorps skr1, anticorps tsri, anticorps xALK-2, anticorps activin A receptor type 1, anticorps activin A receptor, type 1, anticorps activin A receptor type 1 S homeolog, anticorps ACVR1, anticorps Acvr1, anticorps acvr1.S
- Sujet
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Description: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.,
Aliases: FOP, ALK2, SKR1, TSRI, ACTRI, ACVR1A, ACVRLK2
- Poids moléculaire
- 57.2 kDa
- ID gène
- 90
- HGNC
- 6850
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