ACVR1 anticorps (AA 21-120)

N° du produit ABIN5542584

L’anticorps Souris Monoclonal anti-ACVR1 a été validé pour ELISA et FACS. Il convient pour détecter ACVR1 dans des échantillons de Humain.

Aperçu rapide pour ACVR1 anticorps (AA 21-120) (ABIN5542584)

Antigène: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACVR1 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 2C1E8

Détail du produit anti-ACVR1 anticorps

Épitope: AA 21-120

Fonction: ACVR1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human ACVR1 (AA: 21-120) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur ACVR1

Antigène: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Autre désignation: ACVR1

Sujet: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.

Poids moléculaire: 57.2 kDa

UniProt: Q04771