Src anticorps
Aperçu rapide pour Src anticorps (ABIN3029562)
Antigène
Voir toutes Src AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified
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Immunogène
- This anti-Src antibody was produced from a mouse immunized with a full length recombinant human protein.
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Isotype
- IgG1
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Indications d'application
- Titration of the anti-Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:100-1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the anti-Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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Autre désignation
- Src
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Sujet
- This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
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UniProt
- P12931
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Pathways
- Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Antigène
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