Caspase 9 anticorps (Ser196)
Aperçu rapide pour Caspase 9 anticorps (Ser196) (ABIN3030322)
Antigène
Voir toutes Caspase 9 (CASP9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Ser196
-
Purification
- Antigen affinity purified
-
Immunogène
- This Caspase-9 antibody was produced from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding S196 of human CASP9.
-
Isotype
- Ig Fraction
-
-
-
-
Indications d'application
- Titration of the Caspase-9 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Aliquot the Caspase-9 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
-
Autre désignation
- Caspase-9
-
Sujet
- Caspase 9 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1, this step is thought to be one of the earliest in the caspase activation cascade.
-
UniProt
- P55211
-
Pathways
- Signalisation MAPK, Signalisation RTK, Apoptose, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity
Antigène
-