GSK3 beta anticorps (AA 4-34)

N° du produit ABIN3031095

Cet anticorps anti-GSK3 beta Polyclonal Lapin (ABIN3031095) détecte spécifiquement GSK3 beta dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GSK3 beta anticorps (AA 4-34) (ABIN3031095)

Antigène: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSK3 beta est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-GSK3 beta anticorps

Épitope: AA 4-34

Fonction: GSK3B Antibody

Réactivité croisée (Details): Expected species reactivity: Mouse, Rat

Purification: Antigen affinity

Immunogène: A portion of amino acids 4-34 from the human protein was used as the immunogen for this GSK3B antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the GSK3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the GSK3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur GSK3 beta

Antigène: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Autre désignation: GSK3B

Sujet: GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]

UniProt: P49841

Pathways: Signalisation WNT, Signalisation Hedgehog, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, L'effet Warburg