PARP1 anticorps (AA 183-214)

N° du produit ABIN3032164

Cet anticorps Lapin Polyclonal détecte spécifiquement PARP1 dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PARP1 anticorps (AA 183-214) (ABIN3032164)

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PARP1 anticorps

Épitope: AA 183-214

Fonction: PARP1 Antibody

Homologie: Mouse

Purification: Purified

Immunogène: A portion of amino acids 183-214 from the human protein was used as the immunogen for this PARP antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the PARP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles

Stock: -20 °C

Stockage commentaire: Aliquot the PARP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur PARP1

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Autre désignation: PARP

Sujet: PARP is a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Additional PARP1 pathway and chromatin-associated DNA repair studies may benefit from our PARP1 antibody page featuring < a href=../tds/parp-antibody-cfd-16-rq5290>recombinant rabbit monoclonal clone CFD-16 with knockdown-validated target recognition.

UniProt: P09874

Pathways: Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location