c-MYC anticorps (pThr58)

N° du produit ABIN3029537

L’anticorps anti-c-MYC Polyclonal Lapin est utilisé pour la détection de c-MYC dans des échantillons de Humain. Il a été validé pour WB, ELISA et DB.

Aperçu rapide pour c-MYC anticorps (pThr58) (ABIN3029537)

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp c-MYC est non-conjugé

Application: Western Blotting (WB), ELISA, Dot Blot (DB)

Détail du produit anti-c-MYC anticorps

Épitope: pThr58

Réactivité croisée (Details): Expected species reactivity: Bovine, Chicken, Mouse, Pig, Rat, Xenopus, Zebrafish

Purification: Antigen affinity purified

Immunogène: This phospho c-Myc antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT58 of human MYC.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho c-Myc antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500,Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS pH 7.4 with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho c-Myc antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur c-MYC

Antigène: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Autre désignation: C-Myc

Sujet: C-Myc participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.

UniProt: P01106

Pathways: Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg