Src anticorps (pTyr215)

N° du produit ABIN3029558

L’anticorps Lapin Polyclonal anti-Src a été validé pour WB et ELISA. Il convient pour détecter Src dans des échantillons de Humain.

Aperçu rapide pour Src anticorps (pTyr215) (ABIN3029558)

Antigène: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Src est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Src anticorps

Épitope: pTyr215

Réactivité croisée (Details): Expected species reactivity: Chicken, Mouse, Rat, Xenopus, Zebrafish

Purification: Antigen affinity purified

Immunogène: This phospho-Src antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY215 of human Src.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the phospho-Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the phospho-Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur Src

Antigène: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Autre désignation: Src

Sujet: This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. Transcript Variant: This variant (1) represents the longer transcript. Both isoforms 1 and 2 encode the same protein.

UniProt: P12931

Pathways: Signalistation JAK/STAT, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling