RBPJ anticorps (AA 1-29)

N° du produit ABIN3032451

Détail du produit anti-RBPJ anticorps

Antigène: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Épitope: AA 1-29

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBPJ est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 1-29 from the human protein was used as the immunogen for this RBPJ antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the RBPJ antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000-2000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the RBPJ antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur RBPJ

Antigène: RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))

Autre désignation: RBPJ (RBPJ Produits)

Synonymes: anticorps AOS3, anticorps CBF1, anticorps IGKJRB, anticorps IGKJRB1, anticorps KBF2, anticorps RBP-J, anticorps RBPJK, anticorps RBPSUH, anticorps SUH, anticorps csl, anticorps AI843960, anticorps Igkjrb, anticorps Igkrsbp, anticorps RBP-J kappa, anticorps RBPjk, anticorps Rbpsuh, anticorps Su(H), anticorps XSu(H), anticorps xsu(h)1, anticorps Su(H)1, anticorps Su(h)A, anticorps ik:tdsubc_1e8, anticorps rbpj, anticorps rbpsuh, anticorps xx:tdsubc_1e8, anticorps Su(H)2, anticorps su(h)B, anticorps recombination signal binding protein for immunoglobulin kappa J region, anticorps recombination signal binding protein for immunoglobulin kappa J region S homeolog, anticorps recombination signal binding protein for immunoglobulin kappa J region a, anticorps recombination signal binding protein for immunoglobulin kappa J region b, anticorps RBPJ, anticorps Rbpj, anticorps rbpj.S, anticorps rbpja, anticorps rbpjb

Sujet: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.

UniProt: Q06330

Pathways: Signalisation Notch, Stem Cell Maintenance, Smooth Muscle Cell Migration