WNT3 anticorps (AA 155-184)

N° du produit ABIN3029628

Détail du produit anti-WNT3 anticorps

Antigène: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Épitope: AA 155-184

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WNT3 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée (Details): Expected species reactivity: Mouse, Chicken, Xenopus

Purification: Antigen affinity purified

Immunogène: A portion of amino acids 155-184 from the human protein was used as the immunogen for this WNT3 antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: Titration of the WNT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the WNT3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur WNT3

Antigène: WNT3 (Wingless-Type MMTV Integration Site Family, Member 3 (WNT3))

Autre désignation: WNT3 (WNT3 Produits)

Synonymes: anticorps INT4, anticorps Ci-Wnt3, anticorps WNT3, anticorps int4, anticorps Xwnt3, anticorps wnt-3, anticorps wnt3l, anticorps Xwnt-3, anticorps wnt3, anticorps Int-4, anticorps Wnt-3, anticorps wnt3-A, anticorps Wnt family member 3, anticorps wingless-type MMTV integration site family, member 3, anticorps proto-oncogene Wnt-3, anticorps wingless-type MMTV integration site family member 3, anticorps Wnt family member 3A, anticorps wingless-type MMTV integration site family member 3 L homeolog, anticorps WNT3, anticorps Wnt3, anticorps wnt3, anticorps LOC468297, anticorps WNT3A, anticorps wnt3.L

Sujet: The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % amino acid identity to mouse Wnt3 protein, and 84 % to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.

UniProt: P56703

Pathways: Signalisation WNT, Regulation of Cell Size