IL12RB1 anticorps (Internal Region)

N° du produit ABIN498037

Détail du produit anti-IL12RB1 anticorps

Antigène: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Épitope: Internal Region

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12RB1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-HVSVKNHSLD SVS

Specificité: This antibody is expected to recognize isoform 1 (NP_005526.1) only.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogène: Peptide with sequence from the Internal region of the protein sequence according to NP_005526.1. Genename: IL12RB1

Information d'application

Indications d'application: Peptide ELISA: Limit Dilution: 1/8000. Western blot: 0.3-1 μg/mL. Approx 100 kDa band observed in Human Peripheral BloodMononucleocytes lysates (calculated MW of 73.0 kDa according to NP_005526.1). Theobserved molecular weight corresponds to the glycosylated form.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IL12RB1

Antigène: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Autre désignation: CD212 / IL12RB1 (IL12RB1 Produits)

Synonymes: anticorps Il12rb, anticorps IL12RB1, anticorps IL-12R, anticorps CD212, anticorps IL-12R-BETA1, anticorps IL12RB, anticorps IL-12R[b], anticorps interleukin 12 receptor subunit beta 1, anticorps interleukin 12 receptor, beta 1, anticorps Il12rb1, anticorps IL12RB1

Sujet: Functions as an interleukin receptor which binds interleukin 12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin 23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.Synonyms: IL-12 receptor beta, IL-12R-beta-1, IL-12RB1, IL12 receptor beta component, Interleukin-12 receptor beta-1 chain

ID gène: 3594

NCBI Accession: NP_005526

UniProt: P42701

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation